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Practice Reading: Fill in the Blanks (Dropdown) ID: #48323 Medical Innovation
Instructions
A  new  study  has  shed  light  on  how  weight-loss  and  diabetes  injections  such  as  Wegovy  and  Ozempic  may  have  wider  medical  benefits  than  we  first  thought.  The  researchers  found  that  these  drugs    on  the  brain  to  lessen  body-wide  inflammation,  which  could  explain  why  they  seem  to  reduce  heart  attacks  more  than    expected  from  their  weight-loss  effects  alone.  The  drugs  belong  to  a  class  of  medications  that  mimic  a  gut  hormone  called  GLP-1,  which  normally  lowers  appetite,  makes  people  feel  full  and    the  release  of  insulin,  a  hormone  involved  in  blood  sugar  regulation.  Several  studies  have  suggested  that,  as  well  as  causing  people  to  lose  weight,  GLP-1  mimics  also  lower  inflammation.  To  investigate  the    behind  this  anti-inflammatory  effect,  the  researchers  conducted  experiments  in  mice.  They  found  that  GLP-1  mimics  reduced  the  animals  inflammatory  response  to  a  bacterial  infection,  but  only  when  the  mice  had  the  receptor  for  GLP-1  on  their  brain  cells.  This  means  that  the  drugs  reduce  inflammation  by  influencing  the  brain,  and  not  just  by    weight  loss.  

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